Kaleena Mosqueda-Lewis has eight points and Bria Hartley has six to lead the Huskies. Breanna Stewart has five points and six rebounds.
UConn twice trailed by two in the half (16-14, 18-16). But the Huskies finished the half with a 12-4 run.
UConn is shooting 38 percent from the field and has 10 turnovers. Penn State is shooting 30 percent with 11 turnovers.